Determinants of exercise calf muscle perfusion in Peripheral Arterial Disease (PAD)

نویسندگان

  • Jorge A Gonzalez
  • Yan Li
  • Peter W Shaw
  • Jennifer Kay
  • Robyn McKenzie
  • David Lopez
  • Aditya Sharma
  • Joseph DiMaria
  • Yang Yang
  • Petroni Gina
  • Michael Salerno
  • Craig H Meyer
  • Frederick H Epstein
  • Brian H Annex
  • Christopher M Kramer
چکیده

Background In patients with PAD, ankle-brachial index (ABI) does not correlate well with time to claudication and lacks the ability to quantify tissue perfusion, therefore limiting the development of new therapies. Arterial spin labeling (ASL) MRI is a novel non-contrast technique that measures peak calf muscle perfusion noninvasively at a microvascular level. We sought to analyze the relationship of traditional risk factors for PAD and levels of exercise-induced calf muscle perfusion measured by ASL MRI.

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عنوان ژورنال:

دوره 18  شماره 

صفحات  -

تاریخ انتشار 2016